Difference Between Vitamin B1 and B12 (With Table)

Vitamins are a very beneficial element that is required in the development and growth of the body of living organisms. Certain types of vitamins can target the particular organs of the body to be developed. Vitamins have been classified based on their micronutrients that are quite necessary to be consumed. Vitamin B1 and B12 are also two such types.

Vitamin B1 vs B12

The main difference between vitamin B1 and B12 is that vitamin B1 is required for the nourishment and growth of the cells in the body. While vitamin B12 is a very necessary component in the metabolism process and also in the nervous system functioning. Both vitamins B1 and B12 belong to the B group of vitamins.

Vitamin B1 is also referred to as thiamine which is naturally found in various types of food. The specialty of vitamin B1 is that it is soluble in water. In some cases, vitamin B1 is added to certain types of food. Vitamin B1 is important in the formation and development of body cells.

Vitamin B12 is also referred to as cobalamin and just like vitamin B1, it is soluble in water. The functioning of vitamin B12 is also involved in the metabolism of multiple types of acids. It is mostly required by animals since their diet consists of several things. Vitamin B12 belongs to the group of B vitamins.

Comparison Table Between Vitamin B1 and B12

Parameters Of Comparison

Vitamin B1

Vitamin B12

Other names

The other names that are used in the place of vitamin B1 are aneurine and thiamine.

The other name and writing formats that are used in the place of vitamin B12 are cobalamin and vitamin B-12.

Scientific formula

In the field of science, the formula used to denote vitamin B1 is C12H17N4OS+.

In the field of science, the formula used to denote vitamin B12 is C₆₃H₈₈CoN₁₄O₁₄P.


Vitamin B1 is required in the development and repairing of the tissues in living organisms.

Vitamin B12 is required for many things such as the nervous system, production of RBC, and brain functionality.

Need for

To release energy from the food that has been consumed, vitamin B1 becomes very essential.

The main work of vitamin B12 involves the regenerating and maturation of cells of nerves that are spread throughout the body.


The sources of vitamin B1 involve peas, liver, bananas, Oranges, bread, cereals, etc. There are many more other sources.

The sources of vitamin B12 include Eggs, Milk, Cottage cheese, Ricotta, Mozzarella, etc.

What is Vitamin B1?

The percentage of Bioavailability of vitamin B1 is from 3.7% to 5.3%. Vitamin B1 can be dissolved in glycerol, methanol, and water. Since it helps the cells to develop and grow, it is considered to be very advantageous for women who are pregnant. Vitamin B1 is known to people by several names such as aneurine and thiamine.

The scientific formula given for vitamin B1 is C12H17N4OS+. It helps in the growth of the baby’s brain and more than that it helps both expecting women and its child to make required energy from carbohydrates. There is a wide range of foods available that are very rich in vitamin B1. For example, milk, eggs, liver, yeast, meat, beef, tuna, salmon, etc.

Chinese medicine texts were the first to record symptoms of vitamin B1 deficiency also known as thiamine deficiency. Another incident was seen in Japan where a physician noticed the rise in the number of deaths of sailors.

He claimed that this scenario of multiple deaths took place because sailors tend to eat only rice constantly for months. This claim was proved positive when the changes in the diet of these sailors brought the number of death down. Vitamin B1 is a very essential nutrient that should be included in the diet on a daily basis.

What is Vitamin B12?

Vitamin B12 generally helps the liver in the process of metabolism. Animals need vitamin B12 in DNA synthesis as a cofactor. A person who is vegetarian can acquire vitamin B12 from plant-based meat, almonds, yeast spreads, tempeh, Fortified Cereals and Soy, Chlorella, etc.

There are two other names used to denote vitamin B12 that are cobalamin and vitamin B-12. Also, the scientific formula given for vitamin B12 is C₆₃H₈₈CoN₁₄O₁₄P. By being a part of myelin synthesis, vitamin B12 helps the nervous system to function normally. It also plays an important role in the maturation of red blood cells that are found in the bone marrow.

The daily amount of vitamin B12 which is recommended for a person to take on a daily basis is 2.4 MG. Even the higher amount of vitamin B12 is not harmful because the body automatically absorbs only the required amount. The remaining amount of vitamin B12 after absorption passes out with urine.

However, if a higher amount of vitamin B12 is being taken to treat the deficiency, sometimes it can cause headaches. Vitamin B12 is considered to be very essential when it comes to the formation and functionality of red blood cells. The deficiency of vitamin B12 can cause Dementia, heart disease, blood vessel disease, etc.

Main Differences Between Vitamin B1 and B12

  1. The important role played by vitamin B1 is in the growth of the body while vitamin B12 plays an important role in the growth of the body and blood cells.
  2. If a person somehow manages to take a high amount of vitamin B1 he might get insomnia or nausea while the higher dose of vitamin B12 can cause skin rash and acne.
  3. Vitamin B1 is also known as thiamine scientifically. Vitamin B12, On the other hand, is also known as cobalamin.
  4. Vitamin B1 is necessary for the repairing of the tissues. On the other hand, vitamin B12 is necessary to increase brain functionality.
  5. There are many vegan sources of vitamin B1 such as cereal, bread, fruits while vitamin B12 has fewer vegan sources.


Vitamins have several types and are considered organic molecules. Vitamins are needed by organisms in small amounts so their body functions can be always on track. The body does not produce vitamins but extracts from multiple fruits, vegetables, and other sources.

But there is some animal that produces necessary vitamin, for example, a dog is capable to produce the required amount of vitamin C. On the other hand, a human has to acquire vitamin C from food.

A proper diet should be taken by a person to be healthy and avoid unnecessary illness and diseases. Every organ needs different types of vitamins to perform several functions.


  1. https://journals.sagepub.com/doi/abs/10.1177/1533210110392941
  2. https://www.nejm.org/doi/full/10.1056/nejmcp1113996